After a week of some injury question marks, the 49ers released their final injury report this afternoon and most everybody we were concerned about is listed as probable. Mike Iupati and Isaac Sopoaga were two question marks at various times this week, but as it currently stands, there is no real reason to think either guy won't play on Sunday.
The most significant Out for the Lions this week would appear to be Tony Scheffler. He has done a bit more blocking than receiving, with Brandon Pettigrew being the prominent pass catcher at tight end. Pettigrew is actually the second leading receiver on the team behind Calvin Johnson with 26 receptions for 279 yards and a touchdown.
We've talked plenty about Megatron, but Donte Whitner and the linebackers could still find themselves with their hands full against Pettigrew. Wide receivers Titus Young and Nate Burleson are difficult matchups as well, but Pettigrew could be the matchup to watch on Sunday.