So I'll keep it brief and talk about the one thing that's different about this game: it's a road game from the 49ers.
During the 2012 regular season, the Niners had four losses. Three of those were on the road. Still, they had a winning road record with 5-3.
The Cardinals, on the other hand, showed a near-dependence on home games. Of their five wins, four were at home (granted, their one road win was against the Patriots -- how did that happen?). Their final road record was 1-7 and their home record was 4-4.
This is my last fan prediction poll. Thanks for all the votes and input, everyone, and thanks to Fooch for offering to put together a piece based on the voting in this series!
As always, here are the stats from the Cardinals last season:
Passing allowed: 200.8 yds/game, 6.5 yds/att
Rushing allowed: 137 yds/game, 4.3 yds/att
Points allowed: 22.3/game