Clearly there is no love lost between coaches Pete Carroll and Jim Harbaugh, Harbaugh being the one who dethroned Carroll from his NCAAF elite status most notably at the "What's Your Deal" game. All of the players denied any animosity or weighty importance placed on this game other than it being the first conference game for both teams.
Just like a boxing match, pound for pound, the Hawks and the Niners match up like no other two teams.
Emotionally enthusiastic coaches: Carroll vs. Harbaugh
Loyal fanatics: The 12th man vs. Niner Nation
Who wins this game is going to come down to who can be more disciplined under pressure, who can make the least mistakes, who will take advantage of the other team's mistakes, the team who is the least distracted by all of the hype placed on this game. After all it's JUST the next game.