I wanted to find out. I didn't have too much time so I started just with the 1st half.
49ers first drive down 7-0
Q1 10:37 2nd and 3
Before: 2 WR formation #81 and #10 left and right respectively, 6 yard cushion on #10, press man on #81
After: At the snap #28, who is guarding #10, backpedals. #10 runs straight up, reduces his cushion and stops - he still has a gap of 3 yards. Pass is thrown way behind him
Result: Incomplete and punt after third down failure. Three and out
49ers third drive 7-7
Q1 1:47 3rd and 4
Before: #10 lined up on the far left with 5 yards of separation, the #23 is actually moving backwards as the ball is snapped.
After: #10 is near the sideline with at least 7 yards of separation from #23. #7 just has to be accurate on the run.
Result: Incomplete and 3 and out.
Q2 12:01 7-7 3rd &7
Before: #11 has a 10 yard cushion
After: #11 has 5 yards separation at this point and he would be even more wide open if he just stays in the space.
Result: Dropped pass. Drive was really a three and out due to a false start on 2nd and 7
Q2 4:25 2nd&9 Down 10-7
Before: Not much separation. #89 is in the slot.
After: #89 running horziontally to #7 right. Perfect passing lane to #89. Instead the ball goes to #81 with three defenders converging on the ball.
Result: Incomplete. 2 plays later 49ers punt.