Well, the first domino has dropped. The San Francisco 49ers announced today that they have signed first-year RB Thomas Clayton to the 53-man roster from the practice squad. To make room on the 53-man roster for Clayton, the 49ers placed WR Arnaz Battle on injured reserve with a foot injury.
While it's always disappointing to lose a guy to injured reserve, the upside to Battle's nagging injuries has been the continued development of the wide receivers, particularly Jason Hill.
Frank Gore remains a game-time decision.
EDITOR'S UPDATE 1:05PM: According to scoresandodds.com, Gore has been downgraded to doubtful. Rotoworld reported there was a chance Gore didn't even make the trip to Miami, but given that he's from there that would surprise me a little bit, if just to see his friends and family. Of course, if the ankle is enough of a problem a cross-country flight probably wouldn't be good for it.