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vs. 
Date: October 7, 2012
Time: 1:25pm PDT
Location: Bill Walsh Field @ Candlestick Park, San Francisco, CA
Odds Shark Spread: 49ers -10
Weather: It's pretty damn nice out
TV Broadcast: FOX - Kenny Albert, Daryl Johnston, Tony Siragusa
Radio: 107.7 The Bone, 680/1050 KNBR - Ted Robinson, Eric Davis
Spanish Radio: KIQI 1010-AM, KATD 990-AM - Erwin Higueros, Juan Carlos Sierra
Compass Media Networks: Chris Carrino, Brian Baldinger
Bills Coverage: Buffalo Rumblings
Injury Report
49ers - Questionable: Brandon Jacobs (knee), Carlos Rogers (ankle), Isaac Sopoaga (ankle, knee); Probable - Andy Lee (hand), NaVorro Bowman (shoulder)
Bills - Out: T Cordy Glenn (ankle), DT Spencer Johnson (ankle), G Kraig Urbik (ankle); Questionable: S Jairus Byrd (hip), WR Ruvell Martin (ankle), G Chad Rinehart (calf); Probable: TE Scott Chandler (head), WR Donald Jones (head)
The 49ers are back home for a three-game home stand, opening it against the Buffalo Bills. The 49ers are a ten point favorite and will be looking to take care of business early. The 49ers were sizable favorites against the Vikings and came out flat, with the Vikings jumping on top and hanging on to the lead. The 49ers will want to avoid that this week against a Bills squad they really should beat.
GO NINERS!