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NFL Picks, Week 10: 49ers face Rams coming out of the bye

We make picks for all 14 NFL games in Week 10

Matt Kartozian-US PRESSWIRE

The 49ers are back from their bye week, which means we get another chance to make picks against the spread and blow a few fake dollars fairly quickly! Last week we did not do well thanks to my decision to take the wrong upsets in a week in which there were few upsets. I went 7-7 for the week in a week in which favorites were 10-4 against the spread. I did happen to go 10-4 straight up, with the difference being my choices to take the Chiefs, Cardinals and Vikings to all cover, but lose to the favorite. Real smart.

The 49ers are sitting as 11 1/2 point favorites, which is only a half point increase from the opening line. Sportsbooks took a bath last week with favorites going 10-4 and drawing a lot of money from bettors. I learned something interesting last week, which is that after taking a big beating, bookies sometimes will extend out the lines a bit under the assumption that bettors coming off a big weekend of favorites are more inclined to double down on the favorites the next week.

Even if bookies are overestimating things, I think the 49ers can cover this line. Even if they focus on the run and control the clock, I think they can put up the kind of points needed to cover this. Sometimes people are a bit hesitant to jump on that kind of spread, but I really think in San Francisco, the 49ers are in a position to handle their business.

Colts (-4.5) @ Jaguars: Colts cover

Raiders @ Ravens (-9): Ravens cover

Broncos (-4.5) @ Panthers: Broncos cover

Giants (-4) @ Bengals: Bengals win outright

Titans @ Dolphins (-6): Dolphins cover

Lions (-1) @ Vikings: Vikings win outright

Bills @ Patriots (-11): Patriots cover

Falcons (-3) @ Saints: Falcons cover

Chargers @ Buccaneers (-3): Bucs cover

Jets @ Seahawks (-6): Seahawks cover

Cowboys (-1.5) @ Eagles: Eagles win outright

Rams @ 49ers (-11.5): 49ers cover

Texans @ Bears (-1): Texans win outright

Chiefs @ Steelers (-12.5): Steelers cover

Overall Record
Versus the spread: 58-70-2
Overall: 87-44