The San Francisco 49ers locker room is open to the media today, and Anthony Davis confirmed to Matt Barrows that he suffered a sprained MCL in the 49ers Week 4 win over the Philadelphia Eagles. Colin Kaepernick was sacked into the back of Davis's leg, and Davis immediately went down. He was able to walk off the field, but was seen with a cane leaving the locker room later that day.
Davis told the media he was not sure if he would play this Monday against the St. Louis Rams. If I had to guess, I would say he sits the game. A sprained MCL varies by player, but we do have one recent example. Left guard Mike Iupati suffered an MCL sprain last season in the 49ers Week 11 loss to the New Orleans Saints. He was subsequently inactive Weeks 12, 13, 14 and 15. He came back for the final two games.
Iupati has always seemed a little more banged up than Davis, so it is possible Davis will not miss nearly as much time with this sprain. However, Iupati's injury likely sets a potential timeline keeping Davis out through the bye week. The 49ers face the Rams this week, and then the Denver Broncos next week. They follow that up with their bye, and then host the Rams in Week 9.