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Reggie Bush downgraded to OUT for 49ers-Cardinals

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The San Francisco 49ers will be without Reggie Bush for a second straight week. He was making progress, according to Jim Tomsula, but is not quite at 100 percent. We break down what it means.

The San Francisco 49ers announced on Saturday that running back Reggie Bush has officially been ruled "Out" for Sunday's game against the Arizona Cardinals. Bush was listed as doubtful on Friday, but the team decided he will remain in Santa Clara to rehab his calf injury.

Bush sat out all three practices this week, which marked the second straight week of that. Jim Tomsula said Friday morning that he was looking really good, but the team had to wait and see what happened during the Friday practice. Tomsula emphasized that Bush would not play if he was only 80 or 90 percent. It would appear that is the case at this point.

Bush's absence means both Jarryd Hayne and Mike Davis will likely be active again behind Carlos Hyde. Davis handled most of the backup running back work against the Steelers, including all the snaps once Hyde left the game to be tested for a concussion (he passed the test). The question now is whether he and Hayne rotate behind Hyde, and if Hayne gets returner snaps. If Bruce Ellington is inactive, DeAndrew White would be the primary competition for work. If Ellington is active, it could be a whole mix of options.