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Predicting the 49ers inactives for Week 12 vs. the Seahawks

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The 49ers have some real decisions to make this time around, thanks to a roster that’s getting healthier.

NFL: San Francisco 49ers at Buffalo Bills Timothy T. Ludwig-USA TODAY Sports

Kyle Shanahan hasn’t had a lot to think about when submitting his list of gameday inactives this season, thanks to a slew of injuries as the San Francisco 49ers teetered on the edge of even having 46 healthy players to make active each day.

In Week 10 before the bye, the 49ers declared OL Darrell Williams, TE George Kittle, WR Trent Taylor, DE Solomon Thomas, DE Aaron Lynch, LB Elijah Lee and LB Pita Taumoepenu inactive. Of those players, Kittle, Taylor, Thomas and Lynch were definitely out due to injury.

Following a bye week and another week of practice, the 49ers only ruled out a single player for Sunday’s game ahead of time: safety Adrian Colbert. That means that he’s the first inactive, while the 49ers will likely also go with Taumoepenu, Lee and Williams once again due to inexperience and lack of roster space.

But all of Thomas, Lynch, Taylor and Kittle practiced this week. All of those players are expected to be healthy enough to return to action, along with defensive end Tank Carradine, who was activated from injured reserve on Saturday.

Then there are defensive linemen Sheldon Day and Cassius Marsh, who were claimed off waivers from the Jacksonville Jaguars and New England Patriots. They are scheme fits and could be active on short notice, though at least one of them should be inactive on Sunday.

It’s possible that both of them will be inactive, with Lynch, Thomas and Carradine all coming back. The team has at least 11 healthy defensive linemen going into Sunday’s game and don’t need that many to be active. Three of the spots could go to defensive linemen.