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49ers vs. Seahawks, Week 2: Game time, TV schedule, online streaming, announcers, depth chart

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The San Francisco 49ers open up the regular season at home against the Seattle Seahawks. Find information here on the 49ers-Seahawks game time, TV channel, live online streaming options, radio, announcers and more!

NFL: Arizona Cardinals at San Francisco 49ers Kirby Lee-USA TODAY Sports

The San Francisco 49ers head on the road in Week 2 for what might be their toughest game of the week. The 49ers travel north to face the Seattle Seahawks at CenturyLink Field. The game kicks off at 1:25 p.m. PT on FOX, with Sam Rosen, David Diehl, and Jen Hale calling the game.

Both teams are looking for their first win of the season. The 49ers were thumped at home by the Carolina Panthers 23-3, thanks to poor offensive line play, and some significant mental mistakes on defense. The Seahawks lost 17-9 on the road against the Green Bay Packers. Their offensive line was the primary culprit in the loss. I guess we’ll see which offensive line is worse on Sunday!

The 49ers are a 14-point underdog in this one, and I am indeed going to lay the points with Seattle. I’m not normally a fan of laying double digit points, but a road game in Seattle does not bode well for the 49ers. I think they could give the Seahawks offense some trouble, but I don’t know how they’re going to get enough points on the board against that defense.

The 49ers head into the game with rookie linebacker Reuben Foster ruled out, and free safety Jimmie Ward listed as questionable. Ward has said he feels 100 percent, and Kyle Shanahan said Friday was his best day of practice thus far. But at the very least, the trainers likely want to see how the hamstring reacts to pre-game warmups. The Seahawks will likely be without linebacker Terence Garvin, who is doubtful with a shoulder injury. Cornerback Richard Sherman is listed as questionable with a hamstring injury, but is expected to play.

Nuts and bolts

49ers depth chart

Location: CenturyLink Field, Seattle, WA
Game time: Sunday, September 17, 1:25 p.m. PT
TV channel: FOX
Online streaming: NFL Game Pass
Radio: 810-AM, 107.7 (Ted Robinson, Tim Ryan) | Full listings
Spanish Radio: KTRB 860-AM (Jesus Zarate, Luis Landero)
Matchup history: Seahawks lead all-time series 22-15
Announcers: Sam Rosen, David Diehl, Jen Hale (sideline)
Enemy blog: Field Gulls
Twitter: @ninersnation
Facebook: Go ahead and give us a like!

Regular season schedule

Week 1: vs. Carolina Panthers - 23-3 LOSS
Week 2: @ Seattle Seahawks, 1:25 p.m., FOX, Sunday, September 17
Week 3: vs. Los Angeles Rams, 5:25 p.m., NFL Network, Thursday, September 21
Week 4: @ Arizona Cardinals, 1:05 p.m., FOX, Sunday, October 1
Week 5: @ Indianapolis Colts, 10:00 a.m., FOX, Sunday, October 8
Week 6: @ Washington, 10:00 a.m., FOX, Sunday, October 15
Week 7: vs. Dallas Cowboys, 1:05 p.m., FOX, Sunday, October 22
Week 8: @ Philadelphia Eagles, 10:00 a.m., FOX, Sunday, October 29
Week 9: vs. Arizona Cardinals, 1:05 p.m., FOX, Sunday, November 5
Week 10: vs. New York Giants, 1:25 p.m., FOX, Sunday, November 12

Week 11: BYE

Week 12: vs. Seattle Seahawks, 1:05 p.m., FOX, November 26
Week 13: @ Chicago Bears, 10:00 a.m., FOX, Sunday, December 3
Week 14: @ Houston Texans, 10:00 a.m., FOX, Sunday, December 10
Week 15: vs. Tennessee Titans, 1:25 p.m., CBS, Sunday, December 17
Week 16: vs. Jacksonville Jaguars, 1:05 p.m., CBS, Sunday, December 24
Week 17: @ Los Angeles Rams, 1:25 p.m., FOX, Sunday, December 31