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49ers vs. Rams, TNF Week 3: Game time, TV schedule, online streaming, announcers, depth chart

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The San Francisco 49ers face the Los Angeles Rams in Week 3, on Thursday Night Football. Find information here on the 49ers-Rams game time, TV channel, live online streaming options, radio, announcers and more!

Dallas Cowboys v San Francisco 49ers Photo by Thearon W. Henderson/Getty Images

The San Francisco 49ers are back home in Week 3, hosting the Los Angeles Rams on Thursday Night Football. The game kicks off at 5:30 p.m. PT on NFL Network, with Mike Tirico and Cris Collinsworth calling the game from the booth, and Heather Cox on the sideline.

The 49ers are coming off a tough loss to the Seattle Seahawks, losing 12-9 up at CenturyLink Field. It was an impressive defensive performance, but the offense failed to show up consistently. Carlos Hyde had 102 rushing yards in the first half, but the offense could not punch it in for the second straight game. The 49ers set a franchise record for longest stretch without a touchdown to open the season.

The Rams opened the season with a beatdown of the Indianapolis Colts, but followed that up by struggling against Washington. They fought back from a 10-point deficit to tie the game, but Kirk Cousins won it late with a touchdown in the closing minutes. Jared Goff is off to a solid start under Sean McVay, but there is still plenty of work for him to do.

The 49ers are a two-point underdog in this game. The line opened with the Rams favored by a field goal, but some early wagering brought it down a point. The 49ers have won three straight against the Rams, and covered the spread in all three wins. In fact, the Rams are the only team the 49ers have beaten since beating the Chicago Bears on December 6, 2015.

The most notable injury for this game is strong safety Eric Reid. He suffered an injury to the PCL in his knee on Sunday against Seattle. He is expected to miss a few weeks. The normal plan would be to move Jaquiski Tartt over to strong safety, but he is questionable with a neck injury. Tartt is expected to play, but we’ll get final word when inactives are announced around 4 p.m. PT.

Nuts and bolts

49ers depth chart

Location: Levi’s Stadium, Santa Clara, CA
Game time: Thursday, September 21, 5:30 p.m. PT
TV channel: NFL Network
Online streaming: NFL Game Pass
Radio: 810-AM, 107.7 (Ted Robinson, Tim Ryan) | Full listings
Spanish Radio: KTRB 860-AM (Jesus Zarate, Luis Landero)
Matchup history: 49ers lead all-time series 68-64-3
Announcers: Mike Tirico, Cris Collinsworth, Heather Cox (sideline)
Enemy blog: Turf Show Times
Twitter: @ninersnation
Facebook: Go ahead and give us a like!

Regular season schedule

Week 1: vs. Carolina Panthers - 23-3 LOSS
Week 2: @ Seattle Seahawks - 12-9 LOSS
Week 3: vs. Los Angeles Rams, 5:25 p.m., NFL Network, Thursday, September 21
Week 4: @ Arizona Cardinals, 1:05 p.m., FOX, Sunday, October 1
Week 5: @ Indianapolis Colts, 10:00 a.m., FOX, Sunday, October 8
Week 6: @ Washington, 10:00 a.m., FOX, Sunday, October 15
Week 7: vs. Dallas Cowboys, 1:05 p.m., FOX, Sunday, October 22
Week 8: @ Philadelphia Eagles, 10:00 a.m., FOX, Sunday, October 29
Week 9: vs. Arizona Cardinals, 1:05 p.m., FOX, Sunday, November 5
Week 10: vs. New York Giants, 1:25 p.m., FOX, Sunday, November 12

Week 11: BYE

Week 12: vs. Seattle Seahawks, 1:05 p.m., FOX, November 26
Week 13: @ Chicago Bears, 10:00 a.m., FOX, Sunday, December 3
Week 14: @ Houston Texans, 10:00 a.m., FOX, Sunday, December 10
Week 15: vs. Tennessee Titans, 1:25 p.m., CBS, Sunday, December 17
Week 16: vs. Jacksonville Jaguars, 1:05 p.m., CBS, Sunday, December 24
Week 17: @ Los Angeles Rams, 1:25 p.m., FOX, Sunday, December 31