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Matt Breida ruled out for the rest of the game with ankle injury

The San Francisco 49ers will be without running back Matt Breida the rest of the day in Week 5, according to FOX announcer Jennifer Hale. Breida suffered an ankle injury in the second quarter when Cardinals safety Budda Baker landed on it. Breida had the ankle taped, but then went to the locker room and did not return. The team formally ruled him out early in the third quarter.

Breida was having a big day, with 56 rushing yards on eight carries. He has been the team’s biggest playmaker out of the backfield in a big way. In Breida’s absence, Alfred Morris becomes the primary lead back, and Raheem Mostert is his backup.

The 49ers do not return to action until Monday Night Football next week, so Breida gets an extra day of rest. If he cannot go in Week 6, the team would likely promote Jeff Wilson from the practice squad. Kyle Shanahan will get a chance to comment on the injury after the game, and we’ll see what Monday testing provides.