Injury report implications for 49ers-Seahawks

The San Francisco 49ers will be without a starter on defense against the Seattle Seahawks Sunday at Levi’s Stadium. Safety Jaquiski Tartt was ruled out Friday by coach Kyle Shanahan, while a handful of players are listed as questionable for the 49ers’ Week 15 matchup.

Tartt’s ailing shoulder continues to torment the 49ers’ safety, who’ll be on the sideline for the second consecutive week. Sunday will be Tartt’s sixth missed game of 2018.

Marcell Harris made his second start of the season in Tartt’s place last week against the Broncos, racking up seven tackles and two tackles for loss. His highlight play came on a fourth-quarter, fourth-down stop in which Broncos quarterback Case Keenum targeted running back Phillip Lindsay in the flat. Harris made the open field tackle and held Lindsay short of the line to gain, stifling the Broncos’ comeback hopes.

It was an excellent rebound for the 49ers’ rookie safety after a rough debut against the Seahawks in Week 13, missing three tackles and contributing to the defense giving up a season-high 168 rushing yards at Century Link Field.

Antone Exum Jr. will likely start at free safety along with Harris.

Receivers Marquise Goodwin and Dante Pettis are listed as questionable for Sunday. Both were limited for Wednesday and Thursday’s practice with calf and foot injuries, respectively.

Tight end George Kittle, coming off a 210-yard performance against the Broncos, figures to shoulder the 49ers’ offense whether Goodwin and Pettis are active or not. In addition to Kittle, second-year receivers Kendrick Bourne and Trent Taylor may also see an increased role.

Running back Matt Breida is among the list of questionable players for Sunday as he steadily recovers from the ankle injury that’s plagued him for most of the season.

Rookie undrafted free agent Jeff Wilson has filled in admirably for Breida, racking up 45 carries for 184 yards over the past three weeks, as well as 10 receptions for 87 yards. He’s likely to have another major role against the Seahawks.

Cornerback K’Waun Williams, after missing last week’s matchup with a knee injury, is also questionable for Week 15.

Rookie defensive back D.J. Reed started in Williams’ place last week and lit up the stat sheet, amassing 12 total tackles, adding three tackles for loss, one sack, one quarterback hit and one forced fumble. It’ll be interesting to see how the 49ers handle Williams’ status, even if healthy. Reed will be hard to keep off the field.

49ers final injury report

Out: S Jaquiski Tartt (shoulder)

Questionable: RB Matt Breida (ankle), WR Marquise Goodwin (calf), DE Cassius Marsh (concussion), LB Mark Nzeocha (groin), WR Dante Pettis (foot), CB K’Waun Williams (knee)

Seahawks final injury report

Out: S Maurice Alexander (concussion), RB Rashaad Penny (knee), LB K.J. Wright (knee)

Doubtful: G D.J. Fluker (hamstring)

Questionable: WR Doug Baldwin (hip), S Bradley McDougald (knee), DT Jarran Reed (oblique)