With Nick Mullens out for the season due to an elbow injury, the Niners will go with third-string quarterback C.J. Beathard, who is making his first start since Week 8 of the 2018 NFL season.
The Niners’ offense will get a big boost with the return of superstar tight end George Kittle but will be without running back Raheem Mostert, who was placed on injured reserve while dealing with an ankle injury.
This game is a big one for the Cardinals, who are trying to lock down the final playoff spot in the NFC. Arizona is 8-6 and sits a game up on the Chicago Bears, but could also move up the standings over the final two weeks.
The Cardinals are a game behind the Tampa Bay Buccaneers and Los Angeles Rams in the NFC standings.
This is your first half open thread.
Game: San Francisco 49ers @ Arizona Cardinals
Time: 1:30 p.m. PT
TV: KNTV (In San Francisco market), Amazon Prime Video
Broadcast team: KNTV: Andrew Catalon, James Lofton
Amazon: Hannah Storm, Andrea Kremer
Streaming: Fubo TV, Twitch or Yahoo Sports mobile
Location: State Farm Stadium
Betting line: Cardinals (-5), O/U 48.5
Enjoy the game!