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49ers vs. Jaguars: How to watch, stream, game time, and betting odds

The 49ers look for their second two-game winning streak of the season as they travel to Jacksonville

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Indianapolis Colts v San Francisco 49ers Photo by Michael Zagaris/San Francisco 49ers/Getty Images

We will find out whether the 49ers are contenders today as they take on a Jacksonville Jaguars team that competes on defense but doesn’t have enough firepower to stay with the upper echelon teams of the NFL.

As you know, Jacksonville can catch even the best teams sleeping at home. The Bills failed to score a touchdown. The difference between Buffalo and San Francisco is the Niners are playing for their season. They should treat every game as a must-win and aren’t in a position to overlook anybody in the NFL.

San Francisco 49ers (4-5) @ Jacksonville Jaguars (2-7)

Date: Sunday, Nov. 21, 2021
Kickoff: 10 a.m. PT
Location: Jacksonville, FL
Play-by-Play: Chris Myers
Color Analyst: Daryl Johnston
Sideline Reporter: Jen Hale
Network: Fox

Here’s the TV map, courtesy of 506 Sports. If you are in the orange, you’ll get the 49ers/ Jags game in your area.

Live Streaming: FuboTV (Try for free here!)

If you’re struggling to find a stream, then search on Twitter each team’s name or google them, and you’ll have plenty of options available.

Odds: 49ers -6.5 at DraftKings SportsBook

Total: 45.5

For more betting information, please visit DK Nation.

Vegas is suggesting a Niners victory with a score in the ballpark of 26-20.

Odds/lines subject to change. T&Cs apply. See for details.