49ers vs. Cardinals: How to watch, stream, game time, and betting odds

The question ahead of the 49ers and Cardinals game is whether Kyler Murray and DeAndre Hopkins will suit up. We know that A.J. Green is out as he’s on the COVID-19 list, so Arizona is already short-handed at wide receiver.

The 49ers have gone from 2.5-point underdogs over at DraftKings Sportsbook to 3-point favorites as of Saturday night. That line movement suggests the Cardinals will be without both Murray and Hopkins.

Arizona Cardinals (7-1 ) @ San Francisco 49ers (3-4)

Date: Sunday, November 7, 2021

Kickoff: 1:25 p.m. PT

Location: Santa Clara, CA

Network: Fox

• Play-by-Play: Kevin Kugler
• Color Analyst: Mark Sanchez
• Sideline Reporter: Laura Okmin

Here’s a look at the TV map, courtesy of 506 Sports:

Green Bay and Kansas City will dominate the afternoon slate as networks wanted “Rodgers versus Mahomes.” Oops.

Live streaming: FuboTV (Try for free here!)

If you’re struggling to find a stream, then search on Twitter each team’s name or google them, and you’ll have plenty of options available.

Odds: 49ers -3, according to DraftKings Sportsbook.

Total: O/U 45

For more betting information, please visit DK Nation.

Vegas is predicting the 49ers to win with a score in the ballpark of 24-20. DeMeco Ryans won’t be happy if his defense allows 20 points to Colt McCoy or a hobbled Murray without his targets. We’ll find out 90 minutes before kickoff if Murray or Hopkins suits up.